Human myogenic reserve cells are quiescent stem cells that contribute to muscle regeneration after intramuscular transplantation in immunodeficient mice

T Laumonier, F Bermont, P Hoffmeyer, V Kindler… - Scientific reports, 2017 - nature.com
… with reduced regenerative potential. In the present study, we investigated if human myogenic
reserve cells (MRC) obtained in vitro, represented a reliable cell source for muscle repair. …

Human skeletal muscle–derived CD133+ cells form functional satellite cells after intramuscular transplantation in immunodeficient host mice

J Meng, S Chun, R Asfahani, H Lochmüller, F Muntoni… - Molecular Therapy, 2014 - cell.com
… of forming myotubes and reserve satellite cells in vitro. They … Some donor-derived satellite
cells expressed the myogenic … they are activated, rather than quiescent, and are therefore to …

In vivo myogenic potential of human CD133+ muscle-derived stem cells: a quantitative study

E Negroni, I Riederer, S Chaouch, M Belicchi, P Razini… - Molecular Therapy, 2009 - cell.com
… to quiescence and will restore the reserve pool of satellite cells under the … immunodeficient
mouse strains as recipients for human … , when injected intramuscularly, are significantly more …

[PDF][PDF] Human satellite cell transplantation and regeneration from diverse skeletal muscles

X Xu, KJ Wilschut, G Kouklis, H Tian, R Hesse… - Stem cell reports, 2015 - cell.com
reserve capable of fiber maintenance and repair. … the fact that most human muscle is quiescent
with little proliferation … that do not exhibit CD56 and CD29 co-expression have myogenic

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

BD Cosgrove, PM Gilbert, E Porpiglia, F Mourkioti… - Nature medicine, 2014 - nature.com
… of cell cycle–arrested (quiescent and senescent) cells within … Before transplantation,
we anesthetized NOD-SCID mice … We stained cells with a mouse monoclonal anti-myogenin

Long-term contribution of human bone marrow mesenchymal stromal cells to skeletal muscle regeneration in mice

AS De La Garza-Rodea, I Van Der Velde… - … Transplantation, 2011 - journals.sagepub.com
… for human spectrin suggests myogenic reprogramming of … to skeletal muscle injury, the
normally quiescent satellite cells get … was studied in CTX-injured TAMs of NOD/SCID mice. LacZ-…

Geriatric muscle stem cells switch reversible quiescence into senescence

P Sousa-Victor, S Gutarra, L García-Prat… - Nature, 2014 - nature.com
transplanted into muscles of young immunodeficient mice. … 10 pfu per muscle was delivered
intramuscularly. CTX injection in … reserve satellite cells to undergo new myogenesis and self-…

Adult stem cells and skeletal muscle regeneration

D Costamagna, E Berardi, G Ceccarelli… - Current gene …, 2015 - ingentaconnect.com
… of muscle fibers [19] as quiescent unipotent stem cells. When … into immunodeficient mice,
facilitated the migration of BM-… in myogenic progenitor cells promote maturation of muscle fibers…

Muscle stem/progenitor cells and mesenchymal stem cells of bone marrow origin for skeletal muscle regeneration in muscular dystrophies

A Klimczak, U Kozlowska, M Kurpisz - Archivum immunologiae et …, 2018 - Springer
… When SCs move out from the quiescence niche, they interact … stem cells of myogenic origin
in an immunodeficient mouse model … The human myogenic reserve cells generated in vitro …

Sources for skeletal muscle repair: from satellite cells to reprogramming

D Sirabella, L De Angelis, L Berghella - … cachexia, sarcopenia and muscle, 2013 - Springer
… , show myogenic potential in vitro and upon transplantation [… and no other myogenic marker
in the quiescent state. When … were transplanted in sarcoglican-null immunodeficient mice